COVID-19

JHLT COVID-19 Rapid Response Articles

  • 1.  JHLT COVID-19 Rapid Response Articles

    Posted 03-12-2020 20:56
    Edited by Stuart Sweet 03-12-2020 20:57
    Colleagues,

    Mandeep Mehra has shared that JJHLT has instituted a rapid response mechanism to publish any pertinent papers related to the evolving COVID-19 pandemic.  A website has now gone live at www.jhltonline.org with the first described cases of COVID-19 in Heart Transplantation.  You will find these articles in a special section of the JHLT titled "COVID-19 and Cardiothoracic Transplantation" At this time the first case series and an accompanying editorial have been published.  

    Thank you Mandeep for this important work.

     

     



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    Stuart Sweet
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  • 2.  RE: JHLT COVID-19 Rapid Response Articles

    Posted 03-13-2020 02:37
    Dear colleagues,

    Although the publication of this paper poses a new dimension and dilemma to the dictum of refraining from publishing any data of organ transplants in whom there is a heavy suspicion regarding the unethical sourcing of the donors' organs, as the information in it is no doubt an important one today to any physician around the globe who takes care of heart transplant patients, the JHLT was right in accepting it for publication. Unfortunately, sometimes we have to join the devil to save more lives.

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    Prof. Jacob Lavee
    Heart Transplantation Unit
    Sheba Medical Center
    Israel
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  • 3.  RE: JHLT COVID-19 Rapid Response Articles

    Posted 03-13-2020 04:28
    We're going to send our own contribution in terms of single-centre report (conservative and VV ECMO) and overall Italian report (VV ECMO), soon.
    The matter is delicate and impressive. No idea of evolution exists.
    We should all provide personal experiences to get advices, personal feelings and build-up the safest protocol and standards of treatment for such a increasing affected population.
    Thanks ISHLT for such a chance to share our efforts even in a robust scientific way.



    Antonio Loforte

    Bologna S. Orsola University Hospital, Italy




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    Dr. Antonio Loforte, MD, PhD

    Bologna S. Orsola University Hospital, Italy
    +390512149043
    +393384395425
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  • 4.  RE: JHLT COVID-19 Rapid Response Articles

    Posted 03-15-2020 04:13
    As discussed with Mark Slaughter and Aly El Banayosy, in terms of not conservative treatment:
    The ratio results to be : 10 (conservative treatment and on ventilator) / 1 VV ECMO (mechanical treatment). This is the same for all Italian centres, I feel (... and I'm checking and collecting data).
    VV ECMO for younger pts crushing (40 to 55 yy/old) and all obese pts having diabetes too.
    Frail and older pts (>65 yy) no ECMO. Only conservative. This would be rescue in our opinion. Conservative is effective as well. 
    Average time of treatment >15 dd (for both conservative and mechanical strategies).
    Yet, no weaning off from ECMO, no deaths, still ongoing (same for pts on ventilator only without ECMO).
    Mostly adoption of lopinavir/ritonavir. Up to 50% even antibiotica. 
    CT-scan, X-chest ray and respiratory function slowly but very slowly improving. They do need more time than expected. This interstitial lung disease is dramatic. Lung are not stiff as ventilator setting needs but the disease in extensive and with high rate of recurrence. Need of prone position frequent and significative.
    We'll see.
    Let's hope...
    Best
    Antonio






    Dr. Antonio Loforte, MD, PhD

    Bologna S. Orsola University Hospital, Italy
    +390512149043
    +393384395425


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    Antonio Loforte
    Dr
    Bologna
    0512149043
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